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Preterm Labour

 

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The Premature Baby

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Incompetent Cervix Pre-eclampsia IUGR Multiple Gestation Preterm Labour Placenta Previa PROM Rh Disease T2T Transfusion

Labor that begins prior to 37 weeks is defined as preterm labour.  There must be both painful and regular contractions, and a change in the cervix.

Contractions that occur prior to 37 weeks BUT do not change the cervix are called preterm contractions.  Preterm contractions do not usually need to be treated unless the woman is very preterm and the contractions are very frequent and strong.

Signs of preterm labor are:

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Regular cramping-like menses or intermittent back aches.

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Increase in discharge

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Blood discharge

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Increased pelvic pressure

Risks for preterm labor are

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Twins, triplet or more

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Prior preterm delivery (not preterm labor)

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Sexually transmitted diseases

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Placenta previa and abruption (bleeding in the second and third trimesters)

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Severe infections during pregnancy such as pyelonephritis

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Medical complications of pregnancy

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Many women with preterm labor have no risk factors.

Impact on Pregnancy

Preterm labor may result in preterm delivery.

Babies born after 32 weeks do very well in the nursery. They have very high survival, and usually don’t have long term complications.

Most babies born prior to 24 weeks have very little chance of survival.  As pregnancy progresses, the survival rate increases and the chance of permanent problems decreases.

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At 24 weeks, about 50% will survive. 

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50% of survivors will have permanent problems due to being born preterm.

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Babies that are born at hospitals with neonatal intensive care units (NICU) do best.

If a hospital does not have a NICU, women are often transferred prior to delivery of the baby to hospital that has a NICU.

Medications are often used to stop labor.    A common medication is Magnesium Sulfate. It is given through an IV.  A large dose is initially given. It causes a feeling of flushing and nausea. This feeling goes away.  A smaller continuous dose is then given for 12-24 hours or more.  Magnesium Sulfate crosses the placenta, but it does not hurt the fetus.

Oral medications are often used to prevent preterm labor from happening again.  

Research studies have not shown that these medications prolong pregnancy.  These medications will decrease the frequency of contractions, and may make women feel better.  Because oral medications do not prolong pregnancy, many doctors do not use them.

Steroids are often given to help the fetus’ lungs mature quicker. They cross the placenta.  Two steroids are used in the United States: Betamethasone and Dexamethasone. Betamethasone is used more frequently, because fewer doses are needed.  Two shots, usually 24 hours apart are given. The shots are given into the muscle.  Sometimes repeat shots are given after 1 week.  The number of repeat shots that are needed, or even necessity of the repeat shots is unknown.  These steroids will not cause growth of facial hair or muscle development.  Women with diabetes often have very high blood sugars after the steroid shots. This is not a reason to avoid the shots. However, blood sugars will need to be tested frequently, and more insulin may be needed.

Special Considerations

Women in preterm labor are often transferred to hospital with neonatal intensive care units (NICU).    This means being further from family and friends.  Baby’s born at hospitals with a NICU do better.  Women with preterm labor and early dilation of the cervix are sometimes put on bed rest until the pregnancy progresses further.  In extreme cases of cervical dilation, bed rest may be in the hospital.  Bed rest is a frustrating experience. (See separate hand out)

Resource: Dartmouth  

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Last updated:  19 October 2009 14:07